Insights

Additional insights

Publications

  • Lu, M., Ma X, L. R. Castillo-Menendez, J. Gorman, U. Ermel, D. S. Terry, M. Chambers, N. Reichard, K. Wang, J. Grover, B. P. Carman, I. Niki?-Spiegel, A. Finzi, E. A. Lemke, C. Abrams, J. B. Munro, P. D. Kwong, A. B. McDermott, S. C. Blanchard, J. G. Sodroski and Mothes W. "Associating HIV-1 Env trimer structures with functional Env conformational states defined by smFRET analysis," Nature (2019)
  • Ma X, Lu M, Gorman J, Terry DS, Hong X, Zhou Z, Zhao H, Altman RB, Arthos J,Blanchard SC, Kwong PD, Munro JB, Mothes W. “HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations,” eLife7554/eLife.34271 (2018)
  • Munro JB, Gorman J, Ma X, Zhou Z, Arthos J, Burton DR, Koff WC, Courter JR, Smith III AB, Kwong PD, Blanchard SC & Mothes W. “Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions,” Science1126/science.1254426 (2014)
  • Herschhorn A, Ma X, Gu C, Ventura JD, Castillo-Menendez L, Melillo B, Terry DS, Smith AB 3rd, Blanchard SC, Munro JB, Mothes W, Finzi A, Sodroski J. “Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins,” MBio,10.1128/mBio.01598-16 (2016)
  • Herschhorn, A., C. Gu, F. Moraca, Ma X, M. Farrell, A. B. Smith, 3rd, M. Pancera, P. D. Kwong, A. Schon, E. Freire, C. Abrams, S. C. Blanchard, W. Mothes and J. G. Sodroski “The beta20-beta21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions,” Nat Communication 8(1): 1049 (2017)
  • Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O’Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR. “Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody,” Science 352:828-833 (2016)
  • Kwon YD, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, Bailer RT, Chambers M, Chuang GY, Doria-Rose NA, Druz A, Hallen MA, HarnedA, Kirys T, Louder MK, O’Dell S, Ofek G, Osawa K, Prabhakaran M, Sastry M, Stewart-Jones GB, Stuckey J, Thomas PV, Tittley T, Williams C, Zhang B, Zhao H, Zhou Z, Donald BR, Lee LK, Zolla-Pazner S, Baxa U, Schon A, Freire E, Shapiro L, Lee KK, Arthos J, Munro JB, Blanchard SC, Mothes W, Binley JM, McDermott AB, Mascola JR, Kwong PD. “Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV- 1,” Nature structural & molecular biology22:522-531 (2015)
  • Ma X, Zhou S, Wei M, Chen Y, Li J, Xiong W, Jiang S, Pan C. “Phylogenetic and biological analysis of a laboratory-generated gammaretrovirus xenotropic murine leukemia virus-related virus (XMRV),” Virus Genes Oct; 45(2):218-24 (2012)
  • Wang X*, Xiong W*, Ma X*, Wei M, Chen Y, Lu L, Debnath AK, Jiang S, Pan C. “The conserved residue Arg46 in the N-terminal heptad repeat domain of HIV-1gp41 is critical for viral fusion and entry,” PLoS One 7(9):e44874. doi: 10.1371/journal.pone.0044874 (2012)
  • Pan C, Ma X, Jiang S. “What can academia learn from XMRV studies?” Nat Rev Urol. Feb 14;9(3):174; author reply 174. doi: 10.1038/nrurol.2011.225-c1 (2012)