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Fiona Lin, Ph.D.

Technology Specialist

Redwood City, CA
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Fiona Lin, Ph.D. Photo

Background

Fiona Lin, Ph.D., is a Technology Specialist in Fish & Richardson’s Silicon Valley Office. Dr. Lin’s technical background includes organic chemistry, chemical biology, and analytical and formulation sciences, as well as bioprocess development. She has worked on a diverse range of molecular entities including small molecules, peptides and therapeutic proteins, multivalent glycoconjugate vaccines, oligonucleotides, drug delivery systems, and engineered T-cell therapies.  Prior to joining the firm, Dr. Lin had extensive experience working in the pharmaceutical and biotech industry in companies including Genentech, Merck, Pfizer, and a Bay Area startup company.

Education

University of California, Berkeley 2006
Chemistry, Ph.D.


University of North Carolina at Charlotte 2002
Organic Chemistry, M.S.


University of North Carolina at Charlotte 2000
Microbiology, B.S.
magna cum laude


University of North Carolina at Charlotte 2000
Chemistry, B.A.
magna cum laude

Language

  • English
  • Mandarin Chinese
  • Cantonese Chinese

Memberships & Affiliations

American Chemical Society (ACS)
American Association of Pharmaceutical Scientists (AAPS)

Other Distinctions

Patents

“Immunologic compositions for use in pneumococcal vaccines”  Fiona Laichu Lin, Viliam Pavliak, Michael William Pride, Shite Sebastian. US2019/0000952A1 and WO2017/085586A1

Recent Presentations and Speaking Engagements

“Analytical Looks for Better Characterization of Polysaccharide-Conjugate Vaccines, Focus on Labile Functional Groups.” Invited oral presentation, World Vaccine Congress, Washington DC, Apr 2-5, 2018.

“Identification of Common Antigen Determinants of Streptococcus pneumoniae Serogroup 33 Capsular Polysaccharides.” Invited oral presentation, FASEB SRC Microbial Glycobiology Conference, Itasca, IL, Jun 8-13, 2014.

Selected Publications

Kodali, S.; Vinogradov, E.; Lin, F.; Khoury, N.; Hao, L.; Pavliak, V.; Jones, H.; Huebner, J.; Jansen, K. U.; Anderson, A.S.; Donald, R. G. K. “A vaccine approach for the prevention of infections by multidrug resistant E. faecium.” J. Biol. Chem., 2015, 290, 19512-26

Lin, F. L.; Vinogradov, E.; Deng, C.; Zeller, S.; Phelan, L.; Green, B. A.; Jansen, K. U.; Pavliak, V. “Structure elucidation of capsular polysaccharides from Streptococcus pneumoniae serotypes 33C, 33D, and revised structure of serotype 33B.” Carbohydr. Res. 2014, 383, 97-104.

Welch, C. J.; Gong, X.; Cuff, J.; Dolman, S.; Nyrop, J; Lin, F.; Rogers, H. “Online analysis of flowing streams using microflow HPLC.” Orig. Process Res, Dev., 2009, 13, 1022-1025.

Lin, F. L.; Urakami, H.; Guan, Z. “Synthesis and evaluation of novel saccharide-peptide hybrid copolymers as siRNA delivery agents.” Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2008, 49, 1095-1096.

Kumar, P.; Schelle, M. W.; Jain, M.; Lin, F. L.; Petzold, C. J.; Leavell, M. D.; Leary, J. A.; Cox, J. S.; Bertozzi, C. R. “PapA1 and PapA2 are essential acyltransferases in the biosynthesis is Mycobacterial virulence factor sulfolipid-1.” Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 11221-11226.

Lin, F. L.; Hoyt, H. M.; van Halbeek, H.; Bergman, R. G.; Bertozzi, C. R. “Mechanistic investigation of the Staudinger ligation.” J. Am. Chem. Soc. 2005, 127, 2686-2695.

Mougous, J. D.; Petzold, C. J.; Senaratne, R. H.; Lee, D. H.; Akey, D. L.; Lin. F. L.; Munchel, S. E.; Pratt, M. R.; Riley, L. W; Leary, J. A.; Berger, J. M.; Bertozzi, C. R. “Identification, function and structure of the Mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis.” Nat. Struct. Mol. Biol. 2004, 11, 721-729.