Mark E. Wilson, Ph.D.

Education

University of California, Irvine 2019
Synthetic Organic & Peptidomimetic Chemistry , NIH Postdoctoral Fellow

University of California, Davis
Organic Chemistry, Ph.D.

California State University, Sonoma
Chemistry, B.S.

Admissions

• None

Other Distinctions

Selected Publications and Presentations

Graeme C. Freestone, Mark E. Wilson, Lisa McCoy, Andrew Lindstrom “Chemical Tractability of the 5,7- dichloro- 1H-pyrazolo[3,4- c]pyridine core” Manuscript in preparat ion .

Alan P. Kaplan,Terence Keenan, Roderick Scott, Xianbo Zhou, Rusiko Bourchouladze, Andrew J. M cRiner , Mark E. Wilson, Darlene Ro mashko , Regina M iller , Matthew Bietsch, Gary Anderson, Jennifer Stanley, Adia Zhang, Dong Lee, and John Nikpur. “Identifi cat ion of 5-(1-Methyl-5-(trifluoromethyl)-lH-pyrazol-3- yl)thiophene-2-Carboxamides as Novel and Selective Monoamine Oxidase B Inhibitors Used to Improve Memory and Cognition”, ACS Chem . Neurosci . 2017 Dec 20;8(12) :2746-2758

Stephen Antonysamy , Gavin Hirst, Frances Park, Paul Sprengeler, Frank Stap penbeck, Ruo St eensma, Mark Wilson, and Melissa Wong.” Fragment Based Discovery of JAK-2 inhibitors”, Bioorg . M ed. Chem. Lett. 2009 Jan 1;19(1) :279-82

Jeff Blaney, Mark Wilson, “FAST Lead Discovery”, Poster Presentation, Gordon research conference on Medicinal Chemistry 2006

Wilson, M. E.; Nowick, J.S. Chapter in “Synthesis of Peptidomimetics”, Houben-Wey/ E22c, 10.14, Eds M. Goodman et. al., Georg Thieme Varlag, Stuggart; NY, 2002

Wilson, M .E.; Nowick, J.S. “An Efficient Synthesis of N,N’ -Linke d Oligoureas ” Tetrahedron Letters, 1998, 39, 6613-6616

Wilson, M.E.; Paech, K.; Kurth, M.J. “Solvent and Reagent Accessibility within Oligo(ethylene glycol) ether

{PEG) Crosslinked Polystyrene Beads” J. Org. Chem. 1998, 63, 5094-5099

Wilson, M .E.; Najdi, S.; Krochta, J.M; Hsieh, Y-L; Kurth, M.J. “Complexation of Borate with Poly{l{­ (acrylamido)-1-deoxylactitol” Macromolecules, 1998, 31, 4486-4492

Zhou, W.J., M .E . Wilson, M .J. Kurt h , Y.- L. Hsieh, J. M . Krochta, and C.F. Shoemaker “Synthesis and Properties of a Novel Water-Soluble Lactose-Containing Polymer and its Crosslinked Hydrogels” Macromolecules, 30(23): 7063-7068 (1998)

Wilson, M.E.; Wilson, J.A. ; Kurth, M.J. “Enhanced Site-Isolation in Crosslink-Functionalized Polystyrene Networks” Macromolecules, 1997, 30, 3340-3348

Moon, H.; Eisenberg, S.W.; Wilson, M.E.; Schore, N.E.; Kurth, M.J. “Preparation of Nonracemic 3,5-

disu bstit uted-y-butyrolactone s: An Efficient Sequent Auxilliary for Amide Alkylation and lodolactonization” J. Org. Chem . 1994, 59, 6504-6505

Selected Patents

Venkataiah Bollu, James Breitenbucher, Alan Kaplan, Robert Lemus, Andrew Lindstrom, Troy Vickers, Mark Wilson , James Zapf, Michael I. Weinhouse; US20140275531 A: Substituted Pyridine and Pyrazine Compounds as PDE4 Inhibitors

Alan Ka plan, Terence Keenan, Michael Weinhouse, Mark Wilson, Andrew Lindstrom, William Ri pka, and Mi Chen; WO/ 2012/ 040258: THERAPEUTIC PIPERAZINES

Arnol d, William D.; Bounaud, Pierre ; Chen, Chixu; Eastman, Brian; Gosberg, An dreas; Gradl, Stefan N.; Hopkins, Stephanie; Li, Zhe; McDonald, Ian; Sprengeler, Paul A.; St eensma, Ruo W.; Wilson, Mark E.; US20070287711Al: Fused Ring Heterocycle Kinase Modulators

Bounaud, Pierre -Yves; Hopkins, Stephanie A.; Jeffer son, Elizabeth Anne; Wilson, Mark E.; Wong, Melissa S.; Kanouni , Toufi ke; US20070173488Al : Pyrazolothiazole Protein Kinase Modulators

Arnold, William D.; Ch en, Chixu; GradI, Stefan N.; Hopkins, Stephanie A.; St eensma, Ruo W.; Tomimoto, Masaki; Wilson, Mark E.; US20070117800Al: Pyrimidinyl-thiophene Kinase Modulators

Arnold, William D.; Bounaud, Pierre; Gosberg, Andreas; Li, Zhe; M cDonal d, Ian; Steensma, Ruo W.; Wilson, Mark E.; US20070043068Al: Pyrrolo-pyridine Kinase Modulators

Arnol d, William D.; Gosberg, Andreas; Li, Zhe; St eensma, Ruo W.; Wilson, Mark E.; US20060035898Al : Fused ring Heterocycle Kinase Modulators

Arnold, William D.; Bounaud, Pierre; Gosberg, Andreas; Li, Zhe; McDonald, Ian; Steensma, Ruo W.; Wilson, Mark E.; US20060030583Al : Pyrrolo-pyridine Kinase Modulators

Cheng, Jie Fei; Chen, M i; Arrhenius, Thomas ; Wilson, Mark E.; Lopaschuk, Gary D.;  Dyck, Jason R.; Serafimov, Rossy; US200500 32828Al : Piperidine Compounds Useful as M alonyl -CoA Decarboxylase Inhibitors

Cheng, Jie Fei; Liu, Bin ; Arrhenius, Thomas ; Wilson, Mark E.; Nadzan, Alex M .; Lopaschuk, Gary D.; Dyck, Jason R. ; Serafimov, Ross y; US20050032824Al: Cyanoguanidine-based Azole Compounds Useful as Malonyl­ CoA Decarboxylase Inhibitors

Kafka, Mark D.; Wilson, Mark E.; Russell, Anna ; Lopaschuk, Gary D.; Dyck, Jason R.; US20050026945Al: Cyanoamide Compounds Useful as Malonyl-CoA Decarboxylase Inhibitors

Arrhenius , Thomas; Cheng, Jie Fei; Wilson, Mark E; Serafimov, Rossy; US20040092503Al : Azoles as Malonyl-coa Decarboxylase Inhibitors Useful as Metabolic Modulators

Arrhenius, Thomas; Ch eng, Jie Fei; Wilson, Mark E.; Serafimov, Rossy; Nishimoto, M asahiro ; Wallace, David Mark; Tith, Sovouthy; Brown, Steve Joel; Harmon, Charles Stanford; US20040082564Al: Methods for Treating Metabolic Diseases Using Malonyl-CoA Decarboxylase Inhibitors