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Sherwin Y. Chan, Ph.D.

Associate

Boston, MA
617-695-7115
schan@fr.com
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Background

Sherwin Chan is an Associate in the Boston office of Fish & Richardson.  Dr. Chan works with large pharmaceutical companies, biotechnology start-ups, and universities, in the preparation and prosecution of patent applications and in strategic portfolio management, specializing in the life sciences and medical devices fields.  His areas of technical expertise include protein and peptide biologics and analytics, nucleic acid therapeutics, antibody technologies, vaccine technologies, and medical devices.

His research experience includes his doctoral dissertation titled, “Function and Regulation of Two Methylenetetrahydrofolate Reductase Isozymes in Saccharomyces cerevisiae.” Upon completion of his dissertation, Dr. Chan continued his studies as a Terry Fox Foundation Postdoctoral Fellow at the Whitehead Institute for Biomedical Research at the Massachusetts Institute of Technology, where he studied epigenetic regulation of genes in S. cerevisiae.  Dr. Chan also has research experience as a research associate at the University of Alberta and Hampshire Chemical Corporation.

Education

J.D., Suffolk University Law School 2015
​Dean’s List​, Distinguished Brief Award​​​​


Ph.D., University of Texas at Austin 2003
Biochemistry


M.S., University of Alberta 1999
Physiology and Cell Biology


B.S., University of Alberta 1995
Biological Sciences

Admissions

  • Massachusetts 2016

Other Distinctions

Selected publications
"Global metabolic changes following loss of a feedback loop reveal dynamic steady states of the yeast metabolome," with P. Lu, A. Rangan, D. R. Appling, D. W. Hoffman, and E. M. Marcotte, Metabolic Engineering 9, 8-20 (2007).

"Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae," with D. R. Appling, Journal of Biological Chemistry 278, 43051-43059 (2003).

"Mammalian mitochondrial initiation factor 2 supports yeast mitochondrial translation without formylated initiator tRNA," with A. S. Tibbetts, L. Oesterlin, G. Kramer, B. Hardesty, and D. R. Appling, Journal of Biological Chemistry 278, 31774-31780 (2003).

"The intracellular distribution of folate derivatives in pea leaves," with E. A. Cossins, Pteridines 14, 17-26 (2003).

"Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo," with S. Roje, F. Kaplan, R. K. Raymond, D. W. Horne, D. R. Appling, and A. D. Hanson, Journal of Biological Chemistry 277, 4056-4061 (2002).

"Cytosolic and mitochondrial enzymes for 10-formylTHF biosynthesis in plants." with L. Chen, F. E. Nargang, and E. A. Cossins, In Chemistry and Biology of Pteridines and Folates 1997 (Pfleiderer, W. and Rokos, H., eds.), pp. 365-368, Blackwell Science, Berlin (1997).

"Distribution of folate derivatives and enzymes for synthesis of 10-formyltetrahydrofolate in cytosolic and mitochondrial fractions of pea leaves," with L. Chen and E. A. Cossins, Plant Physiology 115, 299-309 (1997).

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